2. Gastrointestinal manifestations of hypothyroidism are
biliary dyskinesia
microglossia
the weakening of taste
increased appetite
ulcerative lesions of the gastric mucosa.
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3. A diagnosis of hypothyroidism can be established
basing on anamnesis
basing on ultrasound data
basing on clinical symptoms
only basing on the data of a hormonal study.
4. Amiodarone-induced hypothyroidism is characterized by
higher risk among women
higher risk among people living in a region with iodine deficiency
higher risk among people living in a region with sufficient levels of iodine
lower risk among individuals with concomitant autoimmune thyroiditis
more often the manifest form
more often the subclinical form.
5. Diseases leading to the development of euthyroid pathology syndrome are
gastritis
hand fracture
tonsillitis
chronic heart failure.
6. Cardiac manifestations of hypothyroidism are
arrhythmia
arterial hypertension diastolic
arterial hypertension systolic
bradycardia
heart failure.
7. Laboratory changes characteristic of subclinical hypothyroidism are
TSH normal Т4 free elevated Т3 free elevated
TSH elevated Т4 free normal Т3 free normal
TSH reduced Т4 free normal Т3 free normal
TSH reduced Т4 free elevated Т3 free elevated.
8. Laboratory sign of hypothyroidism is
hypernatremia
dyslipidemia
the increased level of bilirubin
the decline in TSH level.
9. Lethality in hypothyroid coma reaches
100%
20-30%
30-40%
50-80%.
10. Measures that are included in treatment of hypothyroid coma are
2 liters of infusion solutions on the first day
taking thyroid hormones
avoiding prescribing glucocorticosteroids
based on cooling the patient.
11. Treatment of iodine-induced hypothyroidism includes
prescribing of corticosteroids
prescribing preparations of iodine
prescribing thyroid hormones
prescribing of thyreostatics.
12. The mechanism of influence of heparin on the level of thyroid hormones
blocks iodine uptake by the thyroid gland
slows down the conversion of T4 to T3
inhibits the uptake of T4 by cells
reduces the synthesis of thyroid hormones.
13. Neuropsychiatric changes when hypothyroidism
excitement
depression – in 8-17%
psychic attacks
memory impairment
shortening of tendon reflexes.
14. Basic principles of hormone replacement therapy for hypothyroidism:
liothyronine is actively used for the replacement therapy of hypothyroidism
the full therapeutic effect (euthyroidism) is achieved not earlier than after 2-3 months. from the beginning of therapy
the drug of choice is levothyroxine sodium
subjective improvement of the patient's condition with proper treatment of hypothyroidism will occur quickly
the TSH level decreases to normal after 6-8 weeks from the beginning of treatment.
15. The main causes of hypothyroidism in the elderly are
autoimmune thyroiditis
hypothyroidism due to TSH deficiency
hypothyroidism on the background of thyroid neoplasms
treatment with radioactive iodine irradiation of the neck and head
previous thyroid surgery.
16. Features of the clinical picture of hypothyroidism in the elderly:
in the elderly atypical clinical forms of hypothyroidism are more common
in the older age group neurological manifestations of the disease are less common
older patients are more susceptible to myxedematous coma
typical signs of hypothyroidism occur in 50-60% of the elderly.
17. Features of treatment of hypothyroidism in elderly patients and persons with CHD:
the initial dose of thyroxine is 50 mcg per day
if there are clinical and instrumental signs of deterioration of coronary circulation the dose of thyroxine should be increased by 12.5-25 mcg/day
increase in the dose of thyroxine by 12.5-25 mcg / day at intervals of 6-8 weeks
increase in the dose of thyroxine by 25-50 mcg / day at intervals of 2 weeks.
18. Osteopenic syndrome is observed when having
hypothyroidism
diffuse endemic goiter
thyrotoxicosis
nodular goiter
euthyroid.
19. Drugs that increase the need for thyroxine:
amlodipine
iron sulfate
based on aluminum oxide
propranolol
phenobarbital.
20. When having autoimmune thyroiditis, it is necessary to
to avoid the intake of iodine in any quantity
avoid pharmacological doses of iodine
administration of levothyroxine drugs for the prevention of hypothyroidism
perform a puncture of the thyroid gland.
21. A sign of hypothyroidism on the ECG is
high wave amplitude
increasing the R-wave
the shortening of the intervals Р-R Q-T
flattening or absence of a wave Т.
22. Principles of maintenance of secondary hypothyroidism:
control of treatment by free T4 level
the control treatment at the level of TSH
the scheme of levothyroxine administration differs from the treatment for primary hypothyroidism
the goal of secondary hypothyroidism replacement therapy is to maintain TSH levels at the upper limit of normal.
23. The prevalence of hypothyroidism after 65 years among women is
10%
15%
25%
30%.
24. Myxedematous heart syndrome is characterized by
bradycardia
cardialgia
positive T wave on the ECG
systolic hypertension.
25. Situations in which a reduction in the dose of thyroxine is required:
pregnancy
malabsorption
taking estrogens-containing drugs
aging.
26. A situation that requires an increase in the dose of thyroxine is
constipation
excess selenium
stomach surgeries
taking drugs that reduce absorption.
27. Subclinical hypothyroidism may have clinical manifestations, namely
depression
increased weakness fatigue
persistent increase in diastolic blood pressure
improvement of the course of angina pectoris
memory impairment.
28. Tactics for subclinical amiodarone-induced hypothyroidism are
hormone testing should be performed every 1-2 months
levothyroxine replacement therapy is necessary
with the cancellation of amiodarone after 2-3 months. TSH is normalized in 50%
relapse is possible in 36% of patients.
29. Characteristic changes detected in hypothyroidism on the background of CHAIT on ultrasound of the thyroid gland:
hypertrophy of the thyroid gland
hypoechogenicity of thyroid tissue
reducing the volume of the thyroid gland
increased blood flow to the thyroid tissue.
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