1. Autoimmune polyglandular syndrome includes
- hypercorticism
- hyperparathyroidism
- primary hypogonadism
- primary hypothyroidism
- muco-cutaneous candidiasis.
2. Gastrointestinal manifestations of hypothyroidism are
- biliary dyskinesia
- microglossia
- the weakening of taste
- increased appetite
- ulcerative lesions of the gastric mucosa.

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3. A diagnosis of hypothyroidism can be established
- basing on anamnesis
- basing on ultrasound data
- basing on clinical symptoms
- only basing on the data of a hormonal study.
4. Amiodarone-induced hypothyroidism is characterized by
- higher risk among women
- higher risk among people living in a region with iodine deficiency
- higher risk among people living in a region with sufficient levels of iodine
- lower risk among individuals with concomitant autoimmune thyroiditis
- more often the manifest form
- more often the subclinical form.
5. Diseases leading to the development of euthyroid pathology syndrome are
- gastritis
- hand fracture
- tonsillitis
- chronic heart failure.
6. Cardiac manifestations of hypothyroidism are
- arrhythmia
- arterial hypertension diastolic
- arterial hypertension systolic
- bradycardia
- heart failure.
7. Laboratory changes characteristic of subclinical hypothyroidism are
- TSH normal Т4 free elevated Т3 free elevated
- TSH elevated Т4 free normal Т3 free normal
- TSH reduced Т4 free normal Т3 free normal
- TSH reduced Т4 free elevated Т3 free elevated.
8. Laboratory sign of hypothyroidism is
- hypernatremia
- dyslipidemia
- the increased level of bilirubin
- the decline in TSH level.
9. Lethality in hypothyroid coma reaches
- 100%
- 20-30%
- 30-40%
- 50-80%.
10. Measures that are included in treatment of hypothyroid coma are
- 2 liters of infusion solutions on the first day
- taking thyroid hormones
- avoiding prescribing glucocorticosteroids
- based on cooling the patient.
11. Treatment of iodine-induced hypothyroidism includes
- prescribing of corticosteroids
- prescribing preparations of iodine
- prescribing thyroid hormones
- prescribing of thyreostatics.
12. The mechanism of influence of heparin on the level of thyroid hormones
- blocks iodine uptake by the thyroid gland
- slows down the conversion of T4 to T3
- inhibits the uptake of T4 by cells
- reduces the synthesis of thyroid hormones.
13. Neuropsychiatric changes when hypothyroidism
- excitement
- depression – in 8-17%
- psychic attacks
- memory impairment
- shortening of tendon reflexes.
14. Basic principles of hormone replacement therapy for hypothyroidism:
- liothyronine is actively used for the replacement therapy of hypothyroidism
- the full therapeutic effect (euthyroidism) is achieved not earlier than after 2-3 months. from the beginning of therapy
- the drug of choice is levothyroxine sodium
- subjective improvement of the patient's condition with proper treatment of hypothyroidism will occur quickly
- the TSH level decreases to normal after 6-8 weeks from the beginning of treatment.
15. The main causes of hypothyroidism in the elderly are
- autoimmune thyroiditis
- hypothyroidism due to TSH deficiency
- hypothyroidism on the background of thyroid neoplasms
- treatment with radioactive iodine irradiation of the neck and head
- previous thyroid surgery.
16. Features of the clinical picture of hypothyroidism in the elderly:
- in the elderly atypical clinical forms of hypothyroidism are more common
- in the older age group neurological manifestations of the disease are less common
- older patients are more susceptible to myxedematous coma
- typical signs of hypothyroidism occur in 50-60% of the elderly.
17. Features of treatment of hypothyroidism in elderly patients and persons with CHD:
- the initial dose of thyroxine is 50 mcg per day
- if there are clinical and instrumental signs of deterioration of coronary circulation the dose of thyroxine should be increased by 12.5-25 mcg/day
- increase in the dose of thyroxine by 12.5-25 mcg / day at intervals of 6-8 weeks
- increase in the dose of thyroxine by 25-50 mcg / day at intervals of 2 weeks.
18. Osteopenic syndrome is observed when having
- hypothyroidism
- diffuse endemic goiter
- thyrotoxicosis
- nodular goiter
- euthyroid.
19. Drugs that increase the need for thyroxine:
- amlodipine
- iron sulfate
- based on aluminum oxide
- propranolol
- phenobarbital.
20. When having autoimmune thyroiditis, it is necessary to
- to avoid the intake of iodine in any quantity
- avoid pharmacological doses of iodine
- administration of levothyroxine drugs for the prevention of hypothyroidism
- perform a puncture of the thyroid gland.
21. A sign of hypothyroidism on the ECG is
- high wave amplitude
- increasing the R-wave
- the shortening of the intervals Р-R Q-T
- flattening or absence of a wave Т.
22. Principles of maintenance of secondary hypothyroidism:
- control of treatment by free T4 level
- the control treatment at the level of TSH
- the scheme of levothyroxine administration differs from the treatment for primary hypothyroidism
- the goal of secondary hypothyroidism replacement therapy is to maintain TSH levels at the upper limit of normal.
23. The prevalence of hypothyroidism after 65 years among women is
- 10%
- 15%
- 25%
- 30%.
24. Myxedematous heart syndrome is characterized by
- bradycardia
- cardialgia
- positive T wave on the ECG
- systolic hypertension.
25. Situations in which a reduction in the dose of thyroxine is required:
- pregnancy
- malabsorption
- taking estrogens-containing drugs
- aging.
26. A situation that requires an increase in the dose of thyroxine is
- constipation
- excess selenium
- stomach surgeries
- taking drugs that reduce absorption.
27. Subclinical hypothyroidism may have clinical manifestations, namely
- depression
- increased weakness fatigue
- persistent increase in diastolic blood pressure
- improvement of the course of angina pectoris
- memory impairment.
28. Tactics for subclinical amiodarone-induced hypothyroidism are
- hormone testing should be performed every 1-2 months
- levothyroxine replacement therapy is necessary
- with the cancellation of amiodarone after 2-3 months. TSH is normalized in 50%
- relapse is possible in 36% of patients.
29. Characteristic changes detected in hypothyroidism on the background of CHAIT on ultrasound of the thyroid gland:
- hypertrophy of the thyroid gland
- hypoechogenicity of thyroid tissue
- reducing the volume of the thyroid gland
- increased blood flow to the thyroid tissue.
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